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Treatment of Pediatric Movement Disorders

Medication: Selective Serotonin Reuptake Inhibitors (SSRIs)

Selective serotonin reuptake inhibitors are a class of medications used primarily to treat psychiatric disorders, including depression, obsessive-compulsive syndromes, and others. Occasionally, SSRIs are also useful for tic disorders and stereotypies. In addition, some metabolic disorders that affect serotonin have benefit from the use of these medicines. The most common of these medications include fluoxetine (Prozac®), sertraline (Zoloft®), paroxetine (Paxil®), fluvoxamine (Luvox®), and citalopram (Celexa®). These medicines have occasionally been reported to cause chorea or tics. When SSRIs are taken in combination with other types of antidepressants, MAO inhibitors (including selegiline or rasagiline), or migraine medications, it is important to watch for the serious "serotonin syndrome."