Genetics
A variety of genes have been implicated in the cause of myoclonus, particularly those cases that include myoclonus as one feature of a disorder.
Myoclonus dystonia
- 7q21—DYT11, SCGE
- 18p11—DYT15
Myoclonic epilepsy
- 8q24—Familial adult myoclonic epilepsy
- G8363A mutation—MERRF
- 21q22.3—CSTB gene—Unverricht-Lundborg disease
- 6p24—EPM2A, EPM2B—Lafora progressive myoclonic epilepsy
Other
- PRNP H187R—Hereditary Creutzfeldt-Jakob disease
- 3242A>G—MELAS
- 22q11—DiGeorge syndrome
